Alterations of monocarboxylate transporter densities during hypoxia in brain and breast tumour cells

BACKGROUND: Tumour cells are characterized by aerobic glycolysis, which provides biomass for tumour proliferation and leads to extracellular acidification through efflux of lactate via monocarboxylate transporters (MCTs). Deficient and spasm-prone tumour vasculature causes variable hypoxia, which fa...

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Bibliographische Detailangaben
Hauptverfasser: Cheng, Chang, Edin, Nina F. Jeppesen, Lauritzen, Knut H., Aspmodal, Ida, Christoffersen, Stine, Jian, Liu, Rasmussen, Lene Juel, Pettersen, Erik O, Xiaoqun, Gao, Bergersen, Linda H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Netherlands 2012
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Original Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396336/
https://ncbi.nlm.nih.gov/pubmed/22700320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13402-012-0081-9
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