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DNA methylation screening identifies driver epigenetic events of cancer cell survival
Cancer cells typically exhibit aberrant DNA methylation patterns that can drive malignant transformation. Whether cancer cells are dependent on these abnormal epigenetic modifications remains elusive. We used experimental and bioinformatics approaches to unveil genomic regions that require DNA methy...
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主要な著者: | , , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
2012
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3395886/ https://ncbi.nlm.nih.gov/pubmed/22624715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2012.03.045 |
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