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DNA methylation screening identifies driver epigenetic events of cancer cell survival

Cancer cells typically exhibit aberrant DNA methylation patterns that can drive malignant transformation. Whether cancer cells are dependent on these abnormal epigenetic modifications remains elusive. We used experimental and bioinformatics approaches to unveil genomic regions that require DNA methy...

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書誌詳細
主要な著者: De Carvalho, Daniel D., Sharma, Shikhar, You, Jueng Soo, Su, Sheng-Fang, Taberlay, Phillippa C., Kelly, Theresa K., Yang, Xiaojing, Liang, Gangning, Jones, Peter A.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395886/
https://ncbi.nlm.nih.gov/pubmed/22624715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2012.03.045
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