DNA methylation screening identifies driver epigenetic events of cancer cell survival

Cancer cells typically exhibit aberrant DNA methylation patterns that can drive malignant transformation. Whether cancer cells are dependent on these abnormal epigenetic modifications remains elusive. We used experimental and bioinformatics approaches to unveil genomic regions that require DNA methy...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: De Carvalho, Daniel D., Sharma, Shikhar, You, Jueng Soo, Su, Sheng-Fang, Taberlay, Phillippa C., Kelly, Theresa K., Yang, Xiaojing, Liang, Gangning, Jones, Peter A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395886/
https://ncbi.nlm.nih.gov/pubmed/22624715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2012.03.045
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