Cholinergic Abnormalities, Endosomal Alterations and Up-Regulation of Nerve Growth Factor Signaling in Niemann-Pick Type C Disease

BACKGROUND: Neurotrophins and their receptors regulate several aspects of the developing and mature nervous system, including neuronal morphology and survival. Neurotrophin receptors are active in signaling endosomes, which are organelles that propagate neurotrophin signaling along neuronal processe...

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Autors principals: Cabeza, Carolina, Figueroa, Alicia, Lazo, Oscar M, Galleguillos, Carolina, Pissani, Claudia, Klein, Andrés, Gonzalez-Billault, Christian, Inestrosa, Nibaldo C, Alvarez, Alejandra R, Zanlungo, Silvana, Bronfman, Francisca C
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395862/
https://ncbi.nlm.nih.gov/pubmed/22458984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-7-11
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