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Numbl inhibits glioma cell migration and invasion by suppressing TRAF5-mediated NF-κB activation

The Notch signaling regulator Numblike (Numbl) is expressed in the brain, but little is known regarding its role in the pathophysiology of glial cells. In this paper, we report that Numbl expression was down-regulated in high-grade human glioma tissue samples and glioblastoma cell lines. To investig...

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Bibliografski detalji
Glavni autori: Tao, Tao, Cheng, Chun, Ji, Yuhong, Xu, Guangfei, Zhang, Jianguo, Zhang, Li, Shen, Aiguo
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Cell Biology 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395653/
https://ncbi.nlm.nih.gov/pubmed/22593207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-09-0805
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