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Silencing MARCH1 suppresses proliferation, migration and invasion of ovarian cancer SKOV3 cells via downregulation of NF-κB and Wnt/β-catenin pathways

Membrane-associated RING-CH (MARCH) belongs to the family of RING-CH type E3 ubiquitin ligases. MARCH1 ubiquitinates and downregulates MHC class II expression in APCs and targets major players of the immune system. However, the role of MARCH1 in ovarian cancer has not been elucidated. The present st...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncol Rep
Prif Awduron: Meng, Ying, Hu, Jianguo, Chen, Yuhong, Yu, Tinghe, Hu, Lina
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: D.A. Spandidos 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5055210/
https://ncbi.nlm.nih.gov/pubmed/27633480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2016.5076
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