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Silencing MARCH1 suppresses proliferation, migration and invasion of ovarian cancer SKOV3 cells via downregulation of NF-κB and Wnt/β-catenin pathways

Membrane-associated RING-CH (MARCH) belongs to the family of RING-CH type E3 ubiquitin ligases. MARCH1 ubiquitinates and downregulates MHC class II expression in APCs and targets major players of the immune system. However, the role of MARCH1 in ovarian cancer has not been elucidated. The present st...

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Detalhes bibliográficos
Publicado no:Oncol Rep
Main Authors: Meng, Ying, Hu, Jianguo, Chen, Yuhong, Yu, Tinghe, Hu, Lina
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5055210/
https://ncbi.nlm.nih.gov/pubmed/27633480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2016.5076
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