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Numbl inhibits glioma cell migration and invasion by suppressing TRAF5-mediated NF-κB activation

The Notch signaling regulator Numblike (Numbl) is expressed in the brain, but little is known regarding its role in the pathophysiology of glial cells. In this paper, we report that Numbl expression was down-regulated in high-grade human glioma tissue samples and glioblastoma cell lines. To investig...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Tao, Tao, Cheng, Chun, Ji, Yuhong, Xu, Guangfei, Zhang, Jianguo, Zhang, Li, Shen, Aiguo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The American Society for Cell Biology 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395653/
https://ncbi.nlm.nih.gov/pubmed/22593207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-09-0805
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