ES cell potency fluctuates with endogenous retrovirus activity

Embryonic stem (ES) cells are derived from blastocyst stage embryos and are believed to be functionally equivalent to the inner cell mass, which lacks the ability to produce all extraembryonic tissues. Here we report the identification of a rare transient cell population within mouse ES and induced...

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Bibliographic Details
Main Authors: Macfarlan, Todd S., Gifford, Wesley D., Driscoll, Shawn, Lettieri, Karen, Rowe, Helen M., Bonanomi, Dario, Firth, Amy, Singer, Oded, Trono, Didier, Pfaff, Samuel L.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395470/
https://ncbi.nlm.nih.gov/pubmed/22722858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11244
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