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Neuroprotection by IL-6 Is Mediated by STAT3 and Antioxidative Signaling in Ischemic Stroke

BACKGROUND AND PURPOSE: Interleukin-6 (IL-6) has been shown to have a neuroprotective effect in brain ischemic injury. However, its molecular mechanisms are still poorly understood. In this study, we investigated the neuroprotective role of the IL-6 receptor (IL-6R) by IL-6 in the reactive oxygen sp...

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Bibliographic Details
Main Authors: Jung, Joo Eun, Kim, Gab Seok, Chan, Pak H.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395465/
https://ncbi.nlm.nih.gov/pubmed/21940958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.111.626648
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