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Soluble peptide treatment reverses CD8 T cell-induced disease in a mouse model of spontaneous tissue-selective autoimmunity

Transgenic (Tg) mouse models of autoimmunity have been utilized to express model antigens that can be recognized by T cells or by autoantibodies. To identify mechanisms of CD8-mediated tissue-specific autoimmune reactions and to identify potential treatments, we generated a double transgenic (DTg) m...

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Detalhes bibliográficos
Main Authors: Paek, So Yeon, Miyagawa, Fumi, Zhang, Hong, Linton, Jay, Hoover, Shelley, Simpson, R. Mark, Katz, Stephen I
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395362/
https://ncbi.nlm.nih.gov/pubmed/22089830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2011.347
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