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Self-peptides prolong survival in murine autoimmunity via reduced IL-2/IL-7 mediated STAT5-signaling, CD8-coreceptor- and Vα2-downregulation
While the pathogenic role of B cells and CD4 T cells has been studied extensively, less is known about the role of CD8 T cells in autoimmunity and self-tolerance. To evaluate the role of CD8 T cells in autoimmunity and its modulation using self-peptides, we utilized mice expressing soluble ovalbumin...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2730960/ https://ncbi.nlm.nih.gov/pubmed/19675167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900793 |
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