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ABCB5 identifies a therapy-refractory tumor cell population in colorectal cancer patients

Identification and reversal of treatment resistance mechanisms of clinically refractory tumor cells is critical for successful cancer therapy. Here we show that ATP-binding cassette member B5 (ABCB5) identifies therapy-refractory tumor cells in colorectal cancer patients following fluorouracil (5-FU...

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Autors principals: Wilson, Brian J., Schatton, Tobias, Zhan, Qian, Gasser, Martin, Ma, Jie, Saab, Karim R., Schanche, Robin, Waaga-Gasser, Ana-Maria, Gold, Jason S., Huang, Qin, Murphy, George F., Frank, Markus H., Frank, Natasha Y.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395026/
https://ncbi.nlm.nih.gov/pubmed/21652540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-0221
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