Methylation of the calcium channel regulatory subunit α2δ-3 (CACNA2D3) predicts site-specific relapse in oestrogen receptor-positive primary breast carcinomas

BACKGROUND: Calcium is an important intracellular messenger that mediates many biological processes that are relevant to the malignant process. Calcium ion channels are key in controlling the intracellular calcium, and little is known about their role in human cancer. METHODS: We used qPCR and pyros...

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Detalhes bibliográficos
Main Authors: Palmieri, C, Rudraraju, B, Monteverde, M, Lattanzio, L, Gojis, O, Brizio, R, Garrone, O, Merlano, M, Syed, N, Lo Nigro, C, Crook, T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3394973/
https://ncbi.nlm.nih.gov/pubmed/22644305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.231
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