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Pharmacokinetics and Pharmacodynamics of the Reverse Transcriptase Inhibitor Tenofovir and Prophylactic Efficacy against HIV-1 Infection

Antiviral pre-exposure prophylaxis (PrEP) through daily drug administration can protect healthy individuals from HIV-1 infection. While PrEP was recently approved by the FDA, the potential long-term consequences of PrEP implementation remain entirely unclear. The aim of this study is to predict the...

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Detalhes bibliográficos
Main Authors: Duwal, Sulav, Schütte, Christof, von Kleist, Max
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3394807/
https://ncbi.nlm.nih.gov/pubmed/22808148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040382
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