Ładuje się......
Ubiquitylation of Terminal Deoxynucleotidyltransferase Inhibits Its Activity
Terminal deoxynucleotidyltransferase (TdT), which template-independently synthesizes DNA during V(D)J recombination in lymphoid cells, is ubiquitylated by a BPOZ-2/Cul3 complex, as the ubiquitin ligase, and then degraded by the 26 S proteasome. We show here that TdT is ubiquitylated by the Cul3-base...
Zapisane w:
| Główni autorzy: | , , , , , , , , , , , , |
|---|---|
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Public Library of Science
2012
|
| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3394778/ https://ncbi.nlm.nih.gov/pubmed/22808041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039511 |
| Etykiety: |
Dodaj etykietę
Nie ma etykietki, Dołącz pierwszą etykiete!
|