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Resistance to Paclitaxel in a Cisplatin-Resistant Ovarian Cancer Cell Line Is Mediated by P-Glycoprotein

The IGROVCDDP cisplatin-resistant ovarian cancer cell line is also resistant to paclitaxel and models the resistance phenotype of relapsed ovarian cancer patients after first-line platinum/taxane chemotherapy. A TaqMan low-density array (TLDA) was used to characterise the expression of 380 genes ass...

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Autors principals: Stordal, Britta, Hamon, Marion, McEneaney, Victoria, Roche, Sandra, Gillet, Jean-Pierre, O’Leary, John J., Gottesman, Michael, Clynes, Martin
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3394717/
https://ncbi.nlm.nih.gov/pubmed/22792399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040717
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