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Neonatal T-cell maturation and homing receptor responses to Toll-like receptor ligands differ from those of adult naive T cells: relationship to prematurity

INTRODUCTION: Inflammation and infection are associated with premature birth and with activation of the fetal immune system. We hypothesized that exposure to microbial Toll-like receptor (TLR) ligands plays an important role in neonatal T-cell maturation and that early exposure to microbial products...

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Detalhes bibliográficos
Main Authors: Crespo, Maricruz, Martinez, Denise G., Cerissi, Adam, Rivera-Reyes, Brenda, Bernstein, Helene B., Lederman, Michael M., Sieg, Scott F., Luciano, Angel A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3394681/
https://ncbi.nlm.nih.gov/pubmed/22258123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2011.26
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