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Toll-Like Receptor Ligands Induce Human T Cell Activation and Death, a Model for HIV Pathogenesis

BACKGROUND: Recently, heightened systemic translocation of microbial products was found in persons with chronic HIV infection and this was linked to immune activation and CD4(+) T cell homeostasis. METHODOLOGY: We examined here the effects of microbial Toll-like receptor (TLR) ligands on T cell acti...

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Detalhes bibliográficos
Main Authors: Funderburg, Nicholas, Luciano, Angel A., Jiang, Wei, Rodriguez, Benigno, Sieg, Scott F., Lederman, Michael M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2271052/
https://ncbi.nlm.nih.gov/pubmed/18382686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001915
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