Hippocampal Neurogenesis, Cognitive Deficits and Affective Disorder in Huntington's Disease

Huntington's disease (HD) is a neurodegenerative disorder caused by a tandem repeat expansion encoding a polyglutamine tract in the huntingtin protein. HD involves progressive psychiatric, cognitive, and motor symptoms, the selective pathogenesis of which remains to be mechanistically elucidate...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ransome, Mark I., Renoir, Thibault, Hannan, Anthony J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2012
Schlagworte:
Review Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3394391/
https://ncbi.nlm.nih.gov/pubmed/22830053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/874387
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