Pharmacokinetics of linagliptin in subjects with hepatic impairment

AIM: To investigate whether hepatic impairment affects linagliptin pharmacokinetics, pharmacodynamics and tolerability. METHOD: This open label, parallel group, single centre study enrolled patients with mild (n = 8), moderate (n = 9) or severe (n = 8) hepatic impairment and healthy subjects (n = 8)...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Graefe-Mody, Ulrike, Rose, Peter, Retlich, Silke, Ring, Arne, Waldhauser, Lisa, Cinca, Rodica, Woerle, Hans-Juergen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2012
Schlagworte:
Pharmacokinetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3394131/
https://ncbi.nlm.nih.gov/pubmed/22242621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2012.04173.x
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