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L-DOPA-induced dyregulation of extrastriatal dopamine and serotonin and affective symptoms in a bilateral rat model of Parkinson’s disease

Convergent evidence indicates that raphestriatal serotonin (5-HT) neurons can convert and release dopamine (DA) derived from exogenous administration of the pharmacotherapeutic L-3,4-dihydroxyphenyl-L-alanine(L-DOPA) as a treatment for Parkinson’s disease (PD). While aspects of such neuroplasticity...

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Detalhes bibliográficos
Main Authors: Jaunarajs, Karen L. Eskow, George, Jessica A., Bishop, Christopher
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393811/
https://ncbi.nlm.nih.gov/pubmed/22659568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2012.05.052
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