Estrogen Receptor β Activation Impairs Prostatic Regeneration by Inducing Apoptosis in Murine and Human Stem/Progenitor Enriched Cell Populations

Androgen depletion is the primary treatment for prostate disease; however, it fails to target residual castrate-resistant cells that are regenerative and cells of origin of prostate cancer. Estrogens, like androgens, regulate survival in prostatic cells, and the goal of this study was to determine t...

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Detalhes bibliográficos
Main Authors: Hussain, Shirin, Lawrence, Mitchell G., Taylor, Renea A., Lo, Camden Yeung-Wah, BioResource, A. P. C., Frydenberg, Mark, Ellem, Stuart J., Furic, Luc, Risbridger, Gail P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393688/
https://ncbi.nlm.nih.gov/pubmed/22808245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040732
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