Estrogen receptor–β activated apoptosis in benign hyperplasia and cancer of the prostate is androgen independent and TNFα mediated

Prostate cancer (PCa) and benign prostatic hyperplasia (BPH) are androgen-dependent diseases commonly treated by inhibiting androgen action. However, androgen ablation or castration fail to target androgen-independent cells implicated in disease etiology and recurrence. Mechanistically different to...

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Detalhes bibliográficos
Main Authors: McPherson, Stephen J., Hussain, Shirin, Balanathan, Preetika, Hedwards, Shelley L., Niranjan, Birunthi, Grant, Michael, Chandrasiri, Upeksha P., Toivanen, Roxanne, Wang, Yuzhuo, Taylor, Renea A., Risbridger, Gail P.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840300/
https://ncbi.nlm.nih.gov/pubmed/20133657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0905524107
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