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Trypanosoma brucei gambiense Group 1 Is Distinguished by a Unique Amino Acid Substitution in the HpHb Receptor Implicated in Human Serum Resistance

Trypanosoma brucei rhodesiense (Tbr) and T. b. gambiense (Tbg), causative agents of Human African Trypanosomiasis (sleeping sickness) in Africa, have evolved alternative mechanisms of resisting the activity of trypanosome lytic factors (TLFs), components of innate immunity in human serum that protec...

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Hlavní autoři: Symula, Rebecca E., Beadell, Jon S., Sistrom, Mark, Agbebakun, Kehinde, Balmer, Oliver, Gibson, Wendy, Aksoy, Serap, Caccone, Adalgisa
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393672/
https://ncbi.nlm.nih.gov/pubmed/22802982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001728
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