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Trypanosoma brucei gambiense Group 1 Is Distinguished by a Unique Amino Acid Substitution in the HpHb Receptor Implicated in Human Serum Resistance

Trypanosoma brucei rhodesiense (Tbr) and T. b. gambiense (Tbg), causative agents of Human African Trypanosomiasis (sleeping sickness) in Africa, have evolved alternative mechanisms of resisting the activity of trypanosome lytic factors (TLFs), components of innate immunity in human serum that protec...

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Dettagli Bibliografici
Autori principali: Symula, Rebecca E., Beadell, Jon S., Sistrom, Mark, Agbebakun, Kehinde, Balmer, Oliver, Gibson, Wendy, Aksoy, Serap, Caccone, Adalgisa
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393672/
https://ncbi.nlm.nih.gov/pubmed/22802982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001728
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