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TP-RT Domain Interactions of Duck Hepatitis B Virus Reverse Transcriptase in cis and in trans during Protein-Primed Initiation of DNA Synthesis In Vitro

The hepadnavirus reverse transcriptase (RT) has the unique ability to initiate viral DNA synthesis using RT itself as a protein primer. Protein priming requires complex interactions between the N-terminal TP (terminal protein) domain, where the primer (a specific Y residue) resides, and the central...

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Bibliografische gegevens
Hoofdauteurs: Boregowda, Rajeev K., Adams, Christina, Hu, Jianming
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393569/
https://ncbi.nlm.nih.gov/pubmed/22514346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00086-12
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