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Mice Deficient in STAT1 but Not STAT2 or IRF9 Develop a Lethal CD4(+) T-Cell-Mediated Disease following Infection with Lymphocytic Choriomeningitis Virus
Interferon (IFN) signaling is crucial for antiviral immunity. While type I IFN signaling is mediated by STAT1, STAT2, and IRF9, type II IFN signaling requires only STAT1. Here, we studied the roles of these signaling factors in the host response to systemic infection with lymphocytic choriomeningiti...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3393544/ https://ncbi.nlm.nih.gov/pubmed/22496215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.07147-11 |
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