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RmtF, a New Member of the Aminoglycoside Resistance 16S rRNA N7 G1405 Methyltransferase Family

Multidrug-resistant clinical isolate Klebsiella pneumoniae BM4686 was highly resistant to 4,6-disubstituted 2-deoxystreptamines and to fortimicin. Resistance was due to the presence, on the 40-kb non-self-transferable plasmid pIP849, of the rmtF gene which was cotranscribed with the upstream aac(6′)...

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Bibliografiske detaljer
Main Authors: Galimand, Marc, Courvalin, Patrice, Lambert, Thierry
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393463/
https://ncbi.nlm.nih.gov/pubmed/22547620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00660-12
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