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Plasmid-Mediated High-Level Resistance to Aminoglycosides in Enterobacteriaceae Due to 16S rRNA Methylation

A self-transferable plasmid of ca. 80 kb, pIP1204, conferred multiple-antibiotic resistance to Klebsiella pneumoniae BM4536, which was isolated from a urinary tract infection. Resistance to β-lactams was due to the bla(TEM1) and bla(CTX-M) genes, resistance to trimethroprim was due to the dhfrXII ge...

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Bibliografiske detaljer
Main Authors: Galimand, Marc, Courvalin, Patrice, Lambert, Thierry
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC166065/
https://ncbi.nlm.nih.gov/pubmed/12878520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.8.2565-2571.2003
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