Plasmid-Mediated High-Level Resistance to Aminoglycosides in Enterobacteriaceae Due to 16S rRNA Methylation

A self-transferable plasmid of ca. 80 kb, pIP1204, conferred multiple-antibiotic resistance to Klebsiella pneumoniae BM4536, which was isolated from a urinary tract infection. Resistance to β-lactams was due to the bla(TEM1) and bla(CTX-M) genes, resistance to trimethroprim was due to the dhfrXII ge...

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Bibliografische gegevens

Gepubliceerd in:	Antimicrob Agents Chemother
Hoofdauteurs:	Galimand, Marc, Courvalin, Patrice, Lambert, Thierry
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	American Society for Microbiology (ASM) 2003
Onderwerpen:	Mechanisms of Resistance
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC166065/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12878520/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.8.2565-2571.2003
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