Induction of Mycobacterial Resistance to Quinolone Class Antimicrobials

An agar plate assay was developed for detecting the induction of drug-resistant mycobacterial mutants during exposure to inhibitors of DNA gyrase. When Mycobacterium smegmatis on drug-containing agar, resistant colonies arose over a period of 2 weeks. A recA deficiency reduced mutant recovery, consi...

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Autors principals: Malik, Muhammad, Chavda, Kalyan, Zhao, Xilin, Shah, Nirali, Hussain, Syed, Kurepina, Natalia, Kreiswirth, Barry N., Kerns, Robert J., Drlica, Karl
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
Matèries:
Mechanisms of Resistance
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393424/
https://ncbi.nlm.nih.gov/pubmed/22564842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00474-12
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