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Activity of Human Immunodeficiency Virus Type 1 Protease Inhibitors against the Initial Autocleavage in Gag-Pol Polyprotein Processing

Inhibitors of HIV protease have proven to be important drugs in combination anti-HIV therapy. These inhibitors were designed to target mature protease and prevent viral particle maturation by blocking Gag and Gag-Pol processing by mature protease. Currently there are few data assessing the ability o...

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Autors principals: Davis, David A., Soule, Erin E., Davidoff, Katharine S., Daniels, Sarah I., Naiman, Nicole E., Yarchoan, Robert
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393404/
https://ncbi.nlm.nih.gov/pubmed/22508308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00055-12
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