The Initial Step in Human Immunodeficiency Virus Type 1 GagProPol Processing Can Be Regulated by Reversible Oxidation

BACKGROUND: Maturation of human immunodeficiency virus type 1 (HIV-1) occurs upon activation of HIV-1 protease embedded within GagProPol precursors and cleavage of Gag and GagProPol polyproteins. Although reversible oxidation can regulate mature protease activity as well as retrovirus maturation, it...

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Hauptverfasser: Daniels, Sarah I., Davis, David A., Soule, Erin E., Stahl, Stephen J., Tebbs, Irene R., Wingfield, Paul, Yarchoan, Robert
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962637/
https://ncbi.nlm.nih.gov/pubmed/21042582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013595
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