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A Human Papillomavirus (HPV) In Vitro Neutralization Assay That Recapitulates the In Vitro Process of Infection Provides a Sensitive Measure of HPV L2 Infection-Inhibiting Antibodies

Papillomavirus L2-based vaccines have generally induced low-level or undetectable neutralizing antibodies in standard in vitro assays yet typically protect well against in vivo experimental challenge in animal models. Herein we document that mice vaccinated with an L2 vaccine comprising a fusion pro...

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Autori principali: Day, Patricia M., Pang, Yuk-Ying S., Kines, Rhonda C., Thompson, Cynthia D., Lowy, Douglas R., Schiller, John T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393370/
https://ncbi.nlm.nih.gov/pubmed/22593236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00139-12
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