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Does roflumilast decrease exacerbations in severe COPD patients not controlled by inhaled combination therapy? the REACT study protocol

BACKGROUND: Many patients with chronic obstructive pulmonary disease (COPD) continue to suffer exacerbations, even when treated with maximum recommended therapy (eg, inhaled combinations of long-acting β(2)-agonist and high dose inhaled corticosteroids, with or without a long-acting anticholinergic...

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Detalhes bibliográficos
Main Authors: Calverley, Peter MA, Martinez, Fernando J, Fabbri, Leonardo M, Goehring, Udo-Michael, Rabe, Klaus F
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393336/
https://ncbi.nlm.nih.gov/pubmed/22791991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S31100
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