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Wnt/β-catenin signaling in T cell immunity and cancer immunotherapy

Wnt ligands are lipid-modified secreted glycoproteins that regulate embryonic development, cell fate specification and the homeostasis of self-renewing adult tissues. In addition to its well established role in thymocyte development, recent studies have indicated that Wnt/β-catenin signaling is crit...

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Bibliographic Details
Main Authors: Gattinoni, Luca, Ji, Yun, Restifo, Nicholas P.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393131/
https://ncbi.nlm.nih.gov/pubmed/20688898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-0356
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