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Ovarian Abnormalities in a Mouse Model of Fragile X Primary Ovarian Insufficiency

FMR1 premutation (PM) alleles have 55–200 CGG·CCG-repeats in their 5′ UTR. PM carriers are at risk of fragile X–associated tremor and ataxia syndrome (FXTAS). Females are also at risk for FX primary ovarian insufficiency (FXPOI). PM pathology is generally attributed to deleterious properties of tran...

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Bibliografiska uppgifter
Huvudupphovsmän: Hoffman, Gloria E., Le, Wei Wei, Entezam, Ali, Otsuka, Noriyuki, Tong, Zhi-Bin, Nelson, Lawrence, Flaws, Jodi A., McDonald, John H., Jafar, Sanjeeda, Usdin, Karen
Materialtyp: Artigo
Språk:Inglês
Publicerad: SAGE Publications 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393073/
https://ncbi.nlm.nih.gov/pubmed/22470123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1369/0022155412441002
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