DNA Vaccination in the Skin Using Microneedles Improves Protection Against Influenza

In this study, we tested the hypothesis that DNA vaccination in the skin using microneedles improves protective immunity compared to conventional intramuscular (IM) injection of a plasmid DNA vaccine encoding the influenza hemagglutinin (HA). In vivo fluorescence imaging demonstrated the expression...

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Bibliografiska uppgifter
Huvudupphovsmän: Song, Jae-Min, Kim, Yeu-Chun, O, Eunju, Compans, Richard W, Prausnitz, Mark R, Kang, Sang-Moo
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2012
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Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392990/
https://ncbi.nlm.nih.gov/pubmed/22508490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.69
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