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DNA Vaccination in the Skin Using Microneedles Improves Protection Against Influenza
In this study, we tested the hypothesis that DNA vaccination in the skin using microneedles improves protective immunity compared to conventional intramuscular (IM) injection of a plasmid DNA vaccine encoding the influenza hemagglutinin (HA). In vivo fluorescence imaging demonstrated the expression...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3392990/ https://ncbi.nlm.nih.gov/pubmed/22508490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.69 |
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