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fras1 shapes endodermal pouch 1 and stabilizes zebrafish pharyngeal skeletal development

Lesions in the epithelially expressed human gene FRAS1 cause Fraser syndrome, a complex disease with variable symptoms, including facial deformities and conductive hearing loss. The developmental basis of facial defects in Fraser syndrome has not been elucidated. Here we show that zebrafish fras1 mu...

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Detalhes bibliográficos
Main Authors: Talbot, Jared Coffin, Walker, Macie B., Carney, Thomas J., Huycke, Tyler R., Yan, Yi-Lin, BreMiller, Ruth A., Gai, Linda, DeLaurier, April, Postlethwait, John H., Hammerschmidt, Matthias, Kimmel, Charles B.
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392706/
https://ncbi.nlm.nih.gov/pubmed/22782724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.074906
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