STAT3 can serve as a hit in the process of malignant transformation of primary cells

The transcription factor signal transducer and activator of transcription 3 (STAT3) acts downstream of many pro-oncogenic signals, including cytokines, growth factors and oncogenes, and is accordingly constitutively active in a wide variety of tumors that often become addicted to it. Moreover, STAT3...

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Detalhes bibliográficos
Main Authors: Demaria, M, Misale, S, Giorgi, C, Miano, V, Camporeale, A, Campisi, J, Pinton, P, Poli, V
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392629/
https://ncbi.nlm.nih.gov/pubmed/22402588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.20
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