A STAT3-mediated metabolic switch is involved in tumour transformation and STAT3 addiction

The pro-oncogenic transcription factor STAT3 is constitutively activated in a wide variety of tumours that often become addicted to its activity, but no unifying view of a core function determining this widespread STAT3-dependence has yet emerged. We show here that constitutively active STAT3 acts a...

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Autors principals: Demaria, Marco, Giorgi, Carlotta, Lebiedzinska, Magdalena, Esposito, Giovanna, D'Angeli, Luca, Bartoli, Antonietta, Gough, Daniel J., Turkson, James, Levy, David E., Watson, Christine J., Wieckowski, Mariusz R., Provero, Paolo, Pinton, Paolo, Poli, Valeria
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2010
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3006025/
https://ncbi.nlm.nih.gov/pubmed/21084727
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