Macrophage Migration Inhibitory Factor (MIF) is Essential for Inflammatory and Neuropathic Pain and Enhances Pain in Response to Stress

Stress and glucocorticoids exacerbate pain via undefined mechanisms. Macrophage migration inhibitory factor (MIF) is a constitutively expressed protein that is secreted to maintain immune function when glucocorticoids are elevated by trauma or stress. Here we show that MIF is essential for the devel...

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Main Authors: Alexander, Jessica K., Cox, Gina M., Tian, Jin-Bin, Zha, Alicia M., Wei, Ping, Kigerl, Kristina A., Reddy, Mahesh K., Dagia, Nilesh M., Sielecki, Theis, Zhu, Michael X., Satoskar, Abhay R., McTigue, Dana M., Whitacre, Caroline C., Popovich, Phillip G.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2012
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392533/
https://ncbi.nlm.nih.gov/pubmed/22575600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2012.04.018
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