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System x(c)- regulates microglia and macrophage glutamate excitotoxicity in vivo

It is widely believed that microglia and monocyte-derived macrophages (collectively referred to as central nervous system (CNS) macrophages) cause excitotoxicity in the diseased or injured CNS. This view has evolved mostly from in vitro studies showing that neurotoxic concentrations of glutamate are...

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Detalhes bibliográficos
Main Authors: Kigerl, Kristina A., Ankeny, Daniel P., Garg, Sanjay K., Wei, Ping, Guan, Zhen, Lai, Wenmin, McTigue, Dana M., Banerjee, Ruma, Popovich, Phillip G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268895/
https://ncbi.nlm.nih.gov/pubmed/22079587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2011.10.025
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