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Twist1 regulates Ifng expression in T helper 1 cells by interfering with Runx3 function

A transcription factor network that includes STAT4, T-bet and Runx3 promotes the differentiation of T helper type 1 (Th1) cells and inflammatory immune responses. How additional transcription factors regulate the function of Th1 cells has not been defined. In this report we show that the negative re...

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Main Authors: Pham, Duy, Vincentz, Joshua W., Firulli, Anthony B., Kaplan, Mark H.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392532/
https://ncbi.nlm.nih.gov/pubmed/22685315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200854
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