Reproducibility of the Nicotine Metabolite Ratio in Cigarette Smokers

BACKGROUND: The nicotine metabolite ratio (NMR or 3-hydroxycotinine/cotinine) has been used to phenotype CYP2A6-mediated nicotine metabolism. Our objectives were to analyze (a) the stability of NMR in plasma, saliva, and blood in various storage conditions, (b) the relationship between NMRs derived...

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Hlavní autoři: St.Helen, Gideon, Novalen, Maria, Heitjan, Daniel F., Dempsey, Delia, Jacob, Peyton, Aziziyeh, Adel, Wing, Victoria C., George, Tony P., Tyndale, Rachel F., Benowitz, Neal L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392523/
https://ncbi.nlm.nih.gov/pubmed/22552800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-12-0236
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