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Differential idiotype utilization for the in vivo type 14 capsular polysaccharide-specific immunoglobulin responses to intact Streptococcus pneumoniae versus a pneumococcal conjugate vaccine
Murine IgG responses specific for the capsular polysaccharide (PPS14) of Streptococcus pneumoniae type 14 (Pn14) induced in response to intact Pn14 or a PPS14-protein conjugate are both dependent on CD4+ T cell help, but appear to utilize marginal zone versus follicular B cells, respectively. Here w...
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| Huvudupphovsmän: | , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2012
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3392520/ https://ncbi.nlm.nih.gov/pubmed/22706079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200599 |
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