The T4 Phage SF1B Helicase Dda is Structurally Optimized to Perform DNA Strand Separation

Helicases move on DNA via an ATP binding and hydrolysis mechanism coordinated by well-characterized helicase motifs. However, the translocation along ssDNA and the strand separation of dsDNA may be loosely or tightly coupled. Dda is a phage T4 SF1B helicase with sequence homology to the Pif1 family...

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Main Authors: He, Xiaoping, Byrd, Alicia K., Yun, Mi-Kyung, Pemble, Charles W., Harrison, David, Yeruva, Laxmi, Dahl, Christopher, Kreuzer, Kenneth N., Raney, Kevin D., White, Stephen W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392491/
https://ncbi.nlm.nih.gov/pubmed/22658750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.04.013
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