Evaluation of Asymmetric Dimethylarginine, Arginine, and Carnitine Metabolism in Pediatric Sepsis

OBJECTIVE: Increased plasma concentrations of the endogenous nitric oxide (NO) synthase inhibitor, asymmetric dimethylarginine (ADMA), decreased arginine bioavailability, and mitochondrial dysfunction have been reported in adult sepsis. We studied whether ADMA, arginine, and carnitine metabolism (a...

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Main Authors: Weiss, Scott L., Haymond, Shannon, Ranaivo, Hantamalala Ralay, Wang, Deli, De Jesus, Victor R., Chace, Donald H., Wainwright, Mark S.
Format: Artigo
Language:Inglês
Published: 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392424/
https://ncbi.nlm.nih.gov/pubmed/22460770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PCC.0b013e318238b5cd
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