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Lin28 Mediates Paclitaxel Resistance by Modulating p21, Rb and Let-7a miRNA in Breast Cancer Cells

Resistance to chemotherapy is a major obstacle for the effective treatment of cancers. Lin28 has been shown to contribute to tumor relapse after chemotherapy; however, the relationship between Lin28 and chemoresistance remained unknown. In this study, we investigated the association of Lin28 with pa...

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Detalhes bibliográficos
Main Authors: Lv, Kezhen, Liu, Liqun, Wang, Linbo, Yu, Jiren, Liu, Xiaojiao, Cheng, Yongxia, Dong, Minjun, Teng, Rongyue, Wu, Linjiao, Fu, Peifen, Deng, Wuguo, Hu, Wenxian, Teng, Lisong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392258/
https://ncbi.nlm.nih.gov/pubmed/22808086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040008
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