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Cyclosporine Treatment Reduces Oxygen Free Radical Generation and Oxidative Stress in the Brain of Hypoxia-Reoxygenated Newborn Piglets

Oxygen free radicals have been implicated in the pathogenesis of hypoxic-ischemic encephalopathy. It has previously been shown in traumatic brain injury animal models that treatment with cyclosporine reduces brain injury. However, the potential neuroprotective effect of cyclosporine in asphyxiated n...

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Detalhes bibliográficos
Main Authors: Gill, Richdeep S., Lee, Tze-Fun, Liu, Jiang-Qin, Chaudhary, Hetal, Brocks, Dion R., Bigam, David L., Cheung, Po-Yin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392221/
https://ncbi.nlm.nih.gov/pubmed/22792343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040471
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